Full Publication


Fear response-based prediction for stress susceptibility to PTSD-like phenotypes

Min-Jae Jeong, Changhee Lee, Kibong Sung, Jung Hoon Jung, Jung Hung Pyo, Joung-Hun Kim

Molecular Brain, 2020 October

Dopaminergic regulation of nucleus accumbens cholinergic interneurons demarcates susceptibility to cocaine addiction

Joo Han Lee, Efrain A. Ribeiro, Jeongseop Kim, Bumjin Ko, Hope Kronman, Yun Ha Jeong, Jong Kyoung Kim, Patricia H. Janak, Eric J. Nestler, Ja Wook Koo, Joung-Hun Kim

Biological Psychiatry, 2020 May 

Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice

Lee Y, Han NE, Kim W, Kim JG, Lee IB, Choi SJ, Chun H, Seo M, Lee CJ, Koh HY, Kim JH, Baik JH, Bear MF, Choi SY, Yoon BJ.

Mol. Cells 2020 Jan; [Epub ahead of print]


Basal Forebrain Cholinergic-induced Activation of Cholecystokinin Inhibitory Neurons in the Basolateral Amygdala.

Lee S, Kim JH.

Exp Neurobiol.  2019 Jun; 28(3):320-328.

Nanoscale imaging reveals miRNA-mediated control of functional states of dendritic spines.

Park IB, Kim HJ, Kim YK, Hwang HS, Kasai H, Kim JH, Park JW.

Proc Natl Acad Sci U S A.  2019 Apr 25.

Systematic analysis of expression signatures of neuronal subpopulations in the VTA.

Kim HJ, Kim M, Kang B, Yun S, Ryeo SE, Hwang D, Kim JH.

Mol Brain. 2019 Dec 11; 12(1):110.


DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM.

Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A, Park SG.

Cell Reports. 2017 Dec; 21(10):2748-2759.


Alterations in Striatal Circuits Underlying Addiction-Like Behaviors.

Kim HJ, Lee JH, Yun K, Kim JH.

Mol Cells. 2017 Jun 30;40(6):379-385.


Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerization.

Kim SJ, Jeong MJ, Jo HJ, Jung JH, Kaang BK, Choi YB, Kim JH

Sci Rep. 2017 Jun 13;7:3351.


Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation.

Yang YR, Song S, Hwang H, Jung JH, Kim SJ, Yoon S, Hur JH, Park JI, Lee C, Nam D, Seo YK, Kim JH, Rhim H, Suh PG.

Sci Rep. 2017 Apr 3;7:44921.


Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior.

Yang YR, Jung JH, Kim SJ, Hamada K, Suzuki A, Kim HJ, Lee JH, Kwon OB, Lee YK, Kim J, Kim EK, Jang HJ, Kang DS, Choi JS, Lee CJ, Marshall J, Koh HY, Kim CJ, Seok H, Kim SH, Choi JH, Choi YB, Cocco L, Ryu SH, Kim JH, Suh PG.

Mol Psychiatry. 2017 Jan 31. 




Amygdala Circuits for Fear Memory: A Key Role for Dopamine Regulation

Lee JH, Lee S, Kim JH.

Neuroscientist. 2016 Nov 20. pii: 1073858416679936


Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer's Disease

Lee K, Kim H, An K, Kwon OB, Park S, Cha JH, Kim MH, Lee Y, Kim JH, Cho K, Kim HS.

Sci Rep. 2016 Oct 6;6:34433.


Visualization and quantification of microRNA in a single cell using atomic force microscopy.

Koo H, Park I, Lee Y, Kim HJ, Jung JH, Lee JH, Kim Y, Kim JH, Park JW.

J Am Chem Soc. . 2016 Aug 16; 138 (36): 11664–11671. 


Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting

Kim KL, Kim D, Lee S, Kim SJ, Noh JE, Kim JH, Chae YC, Lee JB, Ryu SH.

Nat Commun. 2016 Mar 24;7:11107.


Dopamine-dependent synaptic plasticity in an amygdala inhibitory circuit controls fear memory expression.

Lee JH, Kim JH.

BMB Rep. 2016 Jan;49(1):1-2.




Bidirectional signaling of Neuregulin-2 mediates formation of GABAergic synapses and maturation of Glutamatergic synapses in newborn granule cells of postnatal Hippocampus.

Lee KH, Lee H, Yang CH, Ko JS, Park CH, Woo RS, Kim JY, Sun W, Kim JH, Ho WK, Lee SH.

J Neurosci. 2015 Dec 16;35(50):16479-93.


Dopamine regulation of amygdala inhibitory circuits for expression of learned fear.

Kwon OB, Lee JH, Kim HJ, Lee S, Lee S, Jeong MJ, Kim SJ, Jo HJ, Ko B, Chang S, Park SK, Choi YB, Bailey CH, Kandel ER, Kim JH

Neuron. 2015 Oct 21;88(2):378-89. 




Neuritin can normalize neural deficits of Alzheimer's disease.

An K, Jung JH, Jeong AY, Kim HG, Jung SY, Lee K, Kim HJ, Kim SJ, Jeong TY, Son Y, Kim HS, Kim JH.

Cell Death Dis. 2014 Nov 13;5:e1523.


Reading single DNA with DNA polymerase followed by atomic force microscopy.

Kim Y, Kim ES, Lee Y, Kim JH, Shim BC, Cho SM, Lee JS, Park JW.

J Am Chem Soc. 2014 Oct 1;136(39):13754-60.


Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease.

Choi Y, Lee K, Ryu J, Kim HG, Jeong AY, Woo RS, Lee JH, Hyun JW, Hahn S, Kim JH, Kim HS.

PLoS One. 2014 Aug 7;9(8):e104121.




Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo.

An K, Klyubin I, Kim Y, Jung JH, Mably AJ, O Dowd ST, Lynch T, Kanmert D, Lemere CA, Finan GM, Park JW, Kim TW, Walsh DM, Rowan MJ, Kim JH.

Mol Brain. 2013 Nov 13;6:47. 


Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation.

Kwak Y, Jeong J, Lee S, Park YU, Lee SA, Han DH, Kim JH, Ohshima T, Mikoshiba K, Suh YH, Cho S, Park SK.

J Biol Chem. 2013 Dec 27;288(52):36878-89.


Inhibitory networks of the amygdala for emotional memory.

Lee S, Kim SJ, Kwon OB, Lee JH, Kim JH.

Front Neural Circuits. 2013 Aug 1;7:129. 


Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling.

Budreck EC, Kwon OB, Jung JH, Baudouin S, Thommen A, Kim HS, Fukazawa Y, Harada H, Tabuchi K, Shigemoto R, Scheiffele P, Kim JH. 

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):725-30. 




Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway.

Yoon KJ, Lee HR, Jo YS, An K, Jung SY, Jeong MW, Kwon SK, Kim NS, Jeong HW, Ahn SH, Kim KT, Lee K, Kim E, Kim JH, Choi JS, Kaang BK, Kong YY.

Mol Brain. 2012 Oct 30;5:40.


Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress.

Son H, Banasr M, Choi M, Chae SY, Licznerski P, Lee B, Voleti B, Li N, Lepack A, Fournier NM, Lee KR, Lee IY, Kim J, Kim JH, Kim YH, Jung SJ, Duman RS.

roc Natl Acad Sci U S A. 2012 Jul 10;109(28):11378-83


An activity-regulated microRNA, miR-188, Controls dendritic plasticity and synaptic transmission by downregulating Neuropilin-2.

Lee K, Kim JH, Kwon OB, An K, Ryu J, Cho K, Suh YH, Kim HS

J Neurosci. 2012 Apr 18;32(16):5678-87. 


Astrocyte-originated ATP protects Aβ(1-42)-induced impairment of synaptic plasticity.

Jung ES, An K, Hong HS, Kim JH, Mook-Jung I

J Neurosci. 2012 Feb 29;32(9):3081-7.


Amyloid precursor protein binding protein-1 knockdown reduces neuronal differentiation in fetal neural stem cells.

Hong BH, Ha S, Joo Y, Kim JA, Chang KA, Woo RS, Suh YH, Kim JH, Kim HS.

Neuroreport. 2012 Jan 25;23(2):61-6.




Pathway-specific alteration of synaptic plasticity in Tg2576 mice.

Jung JH, An K, Kwon OB, Kim HS, Kim JH.

Mol Cells. 2011 Aug;32(2):197-201.


Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia.

Choi YB, Li HL, Kassabov SR, Jin I, Puthanveettil SV, Karl KA, Lu Y, Kim JH, Bailey CH, Kandel ER.

Neuron. 2011 May 12;70(3):468-81.


Focal transient ischemia increases APP-BP1 expression in neural progenitor cells.

Joo Y, Lee SH, Ha S, Hong BH, Kim JH, Suh YH, Kim HS

Neuroreport. 2011 Mar 30;22(5):200-5. 


Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine.

Kim J, Park BH, Lee JH, Park SK, Kim JH.

Biol Psychiatry. 2011 Jun 1;69(11):1026-34. 




Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells.

Joo Y, Ha S, Hong BH, Kim JA, Chang KA, Liew H, Kim S, Sun W, Kim JH, Chong YH, Suh YH, Kim HS.

PLoS One. 2010 Dec 2;5(12):e14203.


Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin.

Park YU, Jeong J, Lee H, Mun JY, Kim JH, Lee JS, Nguyen MD, Han SS, Suh PG, Park SK

Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17785-90.


Input-specific synaptic plasticity in the amygdala is regulated by Neuroligin-1 via postsynaptic NMDA receptors.

Jung SY, Kim J, Kwon OB, Jung JH, An K, Jeong AY, Lee CJ, Choi YB, Bailey C, Kandel ER, Kim JH

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4710-5. 




Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in aplysia.

Miniaci MC, Kim JH, Puthanveettil S, Si K, Zhu H, Kandel ER, Bailey C.

Neuron. 2008 Sep 25;59(6):1024-36. 


Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals.

Kim J, Jung SY, Lee YK, Park SK, Choi JS, Lee CJ, Kim HS, Choi YB, Scheiffele P, Bailey C, Kandel ER, Kim JH.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9087-92.